Latest News on Clinical Trials
Could blockchain ensure integrity of clinical trial data?
Prototype web portal shows technology's potential to protect and streamline the clinical trials process UC San Francisco researchers have created a proof-of-concept method for ensuring the integrity of clinical trials data with blockchain. The system creates an...
Antibody therapy training phagocytes to destroy tumors now tested on patients
Developed by researchers at the University of Turku in Finland, an immunotherapeutic antibody therapy re-educates macrophages to activate passivated cytotoxic T cells to kill cancer. The antibody therapy prevented the growth of tumours in several mouse models. The...
New ‘smart drug’ shows promise for metastatic triple-negative breast cancer
A new "smart drug" has shown promise for women with metastatic triple-negative breast cancer, based on data from a clinical trial at NewYork-Presbyterian/Columbia's Herbert Irving Comprehensive Cancer Center and other centers. The data from the trial were published...
Owlstone Medical Partners with Shanghai Renji Hospital to Pioneer Breath Biopsy Lung Cancer Trial in China
Owlstone Medical Ltd., a global diagnostics company developing a breathalyzer for applications in early disease detection and precision medicine, and Renji Hospital, today announced a collaboration to conduct a clinical trial into the early detection of lung cancer...
Satsuma Pharmaceuticals Provides Corporate Update and Prepares to Advance Lead Product Candidate, STS101, Into Phase 3 Efficacy Trial for Acute Migraine
- STS101 for the acute treatment of migraine demonstrates highly differentiated pharmacokinetic (PK) profile in Phase 1 clinical trial - Satsuma successfully completes FDA meeting, establishing key elements of the STS101 Phase 3 development program to support NDA -...
The C Diff Foundation Has Declared an Urgent Need to Raise Clostridium difficile Infection Clinical Trial Awareness Worldwide
The C Diff Foundation announced today that their organization has implemented a global campaign to raise awareness of Clostridioides difficile clinical trials, clinical studies, clinical research and observational studies evaluating interventions for C. difficile...
Mallinckrodt Announces Interim Analysis Results for Therakos® Platform Phase 3 Clinical Trial in Treatment of Pediatric Patients with Steroid Refractory Acute Graft-versus-Host Disease
-- Overall response rate exceeded specified study midpoint target (n=25); company elects to discontinue further patient enrollment as allowed by protocol -- Mallinckrodt plc (NYSE: MNK), a leading global specialty pharmaceutical company, today announced interim...
PPD and HLT to Create Data Science-Driven Clinical Research Solutions in China to Enhance Global Drug Development
Unique collaboration pairs HLT’s data technology and artificial intelligence with PPD’s global expertise in clinical trials and real-world evidence generation Pharmaceutical Product Development, LLC (PPD) and Happy Life Tech (HLT) of China have signed an exclusive...
Shimmer launches Verisense wearable sensor platform for clinical trials
Verisense was designed specifically to improve data quality in clinical trials, while reducing burden on sponsors, sites and participants Shimmer, a global leader in wearable technology for research applications, has announced the launch of Verisense, its...
Torque Initiates Phase 1 Clinical Trial of TRQ-1501 Deep IL-15 Primed T Cells in Patients with Advanced Solid Tumors or Lymphomas
Torque, a clinical-stage immuno-oncology company developing first-in-class Deep Primed™ T Cell Therapeutics to direct immune power deep within the tumor microenvironment, announced today that the first patient has been treated in a Phase 1 clinical trial to evaluate...
ADC Therapeutics Announces First Patient Dosed in Phase I Clinical Trial of ADCT-402 (loncastuximab tesirine) and Ibrutinib in Patients with Advanced Diffuse Large B-Cell Lymphoma or Mantle Cell Lymphoma
Combination trial to evaluate safety and anti-tumor activity of agents that target B-cell cancers ADC Therapeutics, an oncology drug discovery and development company that specializes in the development of proprietary antibody drug conjugates (ADCs), today announced...
Torque Announces Clinical Trial Collaboration with Merck
- Phase 1/2 combination clinical trial evaluating Torque's Deep IL-15 Primed T Cells (TRQ-1501) and KEYTRUDA® (pembrolizumab) for the treatment of multiple cancer indications - Torque, a clinical-stage immuno-oncology company developing first-in-class Deep Primed™ T...
AzurRx BioPharma Announces First Patients Dosed in Phase II OPTION Clinical Trial
Initial top line data of MS1819-SD in Cystic Fibrosis Patients expected in mid-2019. First patients dosed in open-label, cross-over Phase II OPTION study with MS1819-SD for exocrine pancreatic insufficiency in cystic fibrosis. Five clinical trial sites in the U.S....
HFSA Partners With XpertDox To Launch XpertTrial, A Clinical Trial Recruitment Platform, To Accelerate Medical Research
The Heart Failure Society of America (HFSA) and XpertDox today announced the launch of the XpertDox product, XpertTrialTM, a clinical trial search and engagement platform. The XpertTrial platform will provide patients and providers with the most up-to-date information...
AC Immune Announces Anti-Tau Monoclonal Antibody Entering Second Phase 2 Trial in Moderate Alzheimer’s Disease
Study complements ongoing trial in the prodromal to mild population AC Immune SA (NASDAQ: ACIU), a Swiss-based, clinical-stage biopharmaceutical company with a broad pipeline focused on neurodegenerative diseases, today announced that Genentech, a member of the Roche...
Biohaven Enrolls First Patient In Phase 3 Generalized Anxiety Disorder (GAD) Trial Of Troriluzole
- Troriluzole is a third-generation tripeptide prodrug and new chemical entity that modulates glutamate, the most abundant excitatory neurotransmitter in the human body - The therapeutic potential of troriluzole in GAD is supported by clinical and translational...
Xencor Announces Partial Clinical Hold on Phase 1 Study of XmAb14045
Xencor, Inc. (NASDAQ: XNCR), a clinical-stage biopharmaceutical company developing engineered monoclonal antibodies for the treatment of cancer, autoimmune diseases, asthma and allergic diseases, today announced that the U.S. Food and Drug Administration (FDA) has...
Japanese Researchers Will Use Stem Cells to Treat Spinal Cord Injuries in Groundbreaking Clinical Trial
Alex Keown writes: There could a new form of treatment in Japan for spinal cord injuries if a newly-approved clinical trial hits the mark. On Monday, a special committee of the Ministry of Health, Labor and Welfare in Japan approved a clinical research program...
Inventiva Announces Results from Phase IIb Clinical Trial with Lanifibranor in Systemic Sclerosis
DAIX, France I February 18, 2019 I Inventiva (Euronext: IVA), a clinical-stage biopharmaceutical company developing oral small molecule therapies for the treatment of diseases in the areas of fibrosis, lysosomal storage disorders and oncology, today announced the...
Mallinckrodt Announces Interim Analysis Results for Therakos® Platform Phase 3 Clinical Trial in Treatment of Pediatric Patients with Steroid Refractory Acute Graft-versus-Host Disease
-- Overall response rate exceeded specified study midpoint target (n=25); company elects to discontinue further patient enrollment as allowed by protocol -- Mallinckrodt Pharmaceuticals (NYSE: MNK), a leading global specialty pharmaceutical company, today announced...
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