Latest News on Clinical Trials
Allergan Announces Positive Phase 3 ACHIEVE II Trial Results for Ubrogepant Published in The Journal of the American Medical Association
- Pivotal Phase 3 clinical trial reinforced efficacy, safety and tolerability of ubrogepant, an orally-administered CGRP receptor antagonist (gepant) -- -- Acute treatment of migraine with ubrogepant compared with placebo led to significantly greater rates of pain...
Phase 1/2 Clinical Trial Data for IDE196 Presented at Society for Melanoma Research Congress
- Robust enrollment, with 27 total patients enrolled in the Phase 1 dose escalation portion, including 12 patients in MUM DLT cohorts, 14 patients in MUM overflow cohort, and 1 GNA11 cutaneous melanoma patient in non-MUM GNAQ/11 cohort - All 12 patients in DLT cohorts...
Hope Biosciences Receives FDA Approval to Commence Groundbreaking Stem Cell Clinical Trial for Alzheimer’s Disease
Partnering with Altoida, Inc. to Leverage Predictive Digital Biomarkers for Detection of Mild Cognitive Impairment due to Alzheimer’s Disease Hope Biosciences, a clinical stage biotechnology company focused on developing cell-based therapeutics for acute and chronic...
Clinical Trial of Boron Neutron Capture Therapy commences in Japan
The Trial will be conducted in the National Cancer Center Hospital of the National Cancer Center Japan. Image credit- shuttershock.com Cancer Intelligence Care Systems, Inc. (CICS) and STELLA PHARMA CORPORATION will commence a Phase I clinical trial of Boron Neutron...
Bio-Space’s Clinical Trial Review: November 11-15
It was a busy week for clinical trial announcements. Here’s a look. ASLAN Pharmaceuticals announced topline data from its TreeTopp (TREatmEnT OPPortunity with varlitinib in biliary tract cancer) trial in second-line biliary tract cancer (BTC). The drug failed to meet...
Phase 1/2 Clinical Trial Progress for IDE196 to be Presented at Society for Melanoma Research Congress
- Update on Phase 1 Dose-Escalation portion of ongoing Phase 1/2 clinical trial, with specific focus on dosing schema, patient enrollment, and safety data, to be presented at SMR on November 20, 2019 - Phase 2 dose selection and expansion into Phase 2 portion of the...
Bristol-Myers Squibb and Pfizer Announce Randomized, Controlled Trial to Evaluate the Effect of Atrial Fibrillation Screening on Health Outcomes in Older Individuals
PRINCETON, N.J. & NEW YORK--(BUSINESS WIRE)--The Bristol-Myers Squibb-Pfizer Alliance today announced the initiation of a new randomized, controlled study, GUARD-AF (ReducinG stroke by screening for UndiAgnosed atRial fibrillation in elderly inDividuals). The...
Bimekizumab Positive Results Confirmed in Second Phase 3 Psoriasis Study
- The Phase 3 BE READY study, evaluating the efficacy and safety of bimekizumab versus placebo in adults with moderate-to-severe chronic plaque psoriasis, met all primary and ranked secondary endpoints(1) - UCB plans to submit applications to regulatory authorities...
Zealand Pharma completes Phase 3 clinical program for HypoPal® rescue pen, initiates a new Phase 2 clinical proof of concept trial with dasiglucagon, and secures DKK 560 million in additional investment
Zealand Pharma completes Phase 3 clinical program for HypoPal® rescue pen, initiates a new Phase 2 clinical proof of concept trial with dasiglucagon, and secures DKK 560 million in additional investment 2019 Q3 Interim Report Copenhagen, November 14, 2019 – Zealand...
resTORbio Announces That the Phase 3 PROTECTOR 1 Trial of RTB101 in Clinically Symptomatic Respiratory Illness Did Not Meet the Primary Endpoint
- Company stops further development of clinically symptomatic respiratory illness indication but continues development of RTB101 in other aging-related diseases, including Parkinson’s disease -- -- Company remains well funded with $117.3 million in cash, cash...
Liver cancer clinical trial only available in Hawaiʻi
A new University of Hawaiʻi Cancer Center coordinated liver cancer clinical trial opened in Hawaiʻi combining two different immunotherapy medications to combat the aggressive disease. The Phase II clinical trial is only available in Hawaiʻi, a state with one of the...
LUNGevity Foundation Launches Inhale for Life: Clinical Trials Public Service Video and Social Media Campaign During Lung Cancer Awareness Month
Seven Compelling Stories Spotlight the Benefits of Clinical Trial Participation, Access to Life-Saving Medical Advances, and Optimal Lung Cancer Care and Treatment Options WASHINGTON, Nov. 14, 2019 /PRNewswire/ -- LUNGevity, the nation's leading lung cancer-focused...
Todos and Amarantus JV Announces Full Enrollment for Clinical Trial of LymPro Alzheimer’s Blood Test Relationship with Amyloid PET
Topline results expected before the end of Q1/2020 REHOVOT, Israel and NEW YORK, Nov. 14, 2019 (GLOBE NEWSWIRE) -- Todos Medical Ltd. (TOMDF), a clinical-stage in-vitro diagnostics company focused on the development of blood tests for the early detection of cancer and...
Ascendis Pharma Expands TransCon™ PTH Phase 2 PaTH Forward Clinical Trial to Expedite Enrollment of Subjects Previously Treated with NATPARA® in the United States
- Reflects company values and commitment to patients living with hypoparathyroidism - - Top-line data from expanded PaTH Forward Trial expected in first quarter of 2020 - - Company expects to exceed targeted enrollment of 40 subjects - COPENHAGEN, Denmark, Nov. 14,...
American BriVision Announces Issuance of a Full Clinical Study Report (CSR) for ABV-1504 for Major Depressive Disorder Phase II Study
PDC-1421 high-dose data meets primary endpoint on MADRS scale in ITT clinical trial population PDC-1421 low-dose and PDC-1421 high-dose each proved safe, were well-tolerated, and had no serious adverse events associated with them in Phase II clinical trial Company is...
I-Mab Biopharma Receives IND Approval from NMPA to Initiate Clinical Trials for its Anti-GM-CSF Monoclonal Antibody TJM2 in China
SHANGHAI, Nov. 14, 2019 /PRNewswire/ -- I-Mab Biopharma ("I-Mab"), a China and U.S.-based clinical-stage biopharmaceutical company exclusively focused on the discovery and development of novel or highly differentiated biologics in immuno-oncology and autoimmune...
Phase 2b/3 Trial of Livoletide Completes Enrollment of PWS Patients Ages 8 to 65
A Phase 2b/3 clinical trial of livoletide, a treatment candidate for excessive eating in people with Prader-Willi syndrome (PWS), has completed recruitment of participants who are 8 to 65 years old. However, enrollment of patients from 4 to 7 years old is still...
fishbat Provides a Guide for Facilitating Clinical Trial Recruitment
There are numerous steps involved in the clinical trial recruitment process, many of which begin prior to the official "start". From the planning stages to the conclusion of each trial, the work that must be done is nothing short of extensive. Despite the intensity of...
Phase III Clinical Study of Valbenazine for Chorea in Huntington Disease
Huntington Study Group Announces Initiation of Phase III Clinical Study of Valbenazine for the Treatment of Chorea Associated with Huntington Disease. Rochester, NY, November 14, 2019 --(PR.com)-- The Huntington Study Group (HSG), a world leader in spearheading...
VBI Vaccines and Brii Biosciences Initiate Phase 1b/2a Study of BRII-179 (VBI-2601) in Patients with Chronic Hepatitis B Infection
VBI Vaccines (NASDAQ: VBIV) (“VBI”), a commercial-stage biopharmaceutical company developing next-generation infectious disease and immuno-oncology vaccines, and Brii Biosciences (“Brii Bio”), a clinical-stage company committed to serving patients’ needs and improving...
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