Latest News on Clinical Trials
Adastra Pharmaceuticals Announces Positive Interim Data from Phase 1b Clinical Trial of Zotiraciclib in the Treatment of Recurrent Malignant Gliomas
National Cancer Institute (NCI) Study Designed to Investigate Zotiraciclib in Combination with Temozolomide (TMZ) Presented During Poster Session at ASCO 2019 Maximum Tolerated Dose of Zotiraciclib (250mg) Elicits Tumor Reduction, Suggesting Activity in Glioblastoma...
Brooklyn ImmunoTherapeutics Announces Presentation of Ongoing Investigator Sponsored Trial of IRX-2 Regimen Combined with Nivolumab in Recurrent/Metastatic Solid Tumors
Brooklyn ImmunoTherapeutics, a biopharmaceutical company focused on exploring the role that cytokine-based therapy can have in treating patients with cancer, today announced the presentation of an ongoing trial poster at the 2019 American Society of Clinical Oncology...
LYNPARZA® (olaparib) Phase 3 SOLO3 Trial Demonstrated a 72% Objective Response Rate in Patients with Platinum-Sensitive Relapsed Germline BRCA-mutated Advanced Ovarian Cancer Compared to 51% of Patients Receiving Chemotherapy
AstraZeneca and Merck (NYSE:MRK), known as MSD outside the United States and Canada), today presented full results from the Phase 3 SOLO3 trial which evaluated LYNPARZA, compared to chemotherapy, for the treatment of platinum-sensitive relapsed patients with...
Vanessa Research Gains Approval to Conduct Phase II Clinical Trial for Treatment of Rare Pediatric Disease
Study will evaluate safety and efficacy of Shylicine®, the first-ever investigational treatment developed for microvillus inclusion disease HAMDEN, Conn., June 4, 2019 /PRNewswire/ -- Vanessa Research, Inc. (VRI) — a biomedical company founded on the desire to "give...
ASCO 2019: Use of Broader Criteria for Clinical Trial Enrollment Would Double Number of Eligible Patients With Lung Cancer
DEEPER INSIGHTS Correlation of Angiogenesis Biomarkers with Early Metastatic Progression in NSCLC A study looking at 10,500 health records of advanced non-small cell lung cancer (aNSCLC) patients from ASCO’s CancerLinQ database found that the use of expanded clinical...
Verona Pharma Initiates Phase 2 Clinical Trial with Metered Dose Inhaler Formulation of Ensifentrine for Maintenance Treatment of COPD
Ensifentrine delivery via MDI inhalers could dramatically expand clinical utility and commercial opportunity Verona Pharma plc (AIM:VRP) (Nasdaq:VRNA) ("Verona Pharma"), a biopharmaceutical company focused on respiratory diseases, announces the initiation of a Phase 2...
Scholar Rock Announces Positive Final Results from Phase 1 Clinical Trial of SRK-015 in Healthy Volunteers
- SRK-015 was well-tolerated in healthy volunteers across all tested doses, supporting evaluation in the ongoing Phase 2 TOPAZ trial in Spinal Muscular Atrophy (SMA) - Pharmacodynamic results from the completed multiple-ascending dose portion of the trial show...
Arcutis Announces Initiation of Phase 2a Clinical Trial of ARQ-151 as a Potential Topical Treatment for Atopic Dermatitis
ARQ-151 Potential "Best in Class" Topical PDE4 inhibitor ARQ-151 is 50- to 300-fold more potent than approved PDE4 inhibitors Phase 2a Topline Data Anticipated Year End 2019 Westlake Village, CA, June 3, 2019 – Arcutis, Inc., a privately held immuno-dermatology drug...
NantKwest Launches First-in-Human Targeted NK Phase I Clinical Trial of CD19 T-haNK Cell Therapy in Lymphoma Patients
NantKwest Inc. (Nasdaq:NK), a pioneering, next generation, clinical-stage immunotherapy company focused on harnessing the unique power of our immune system using natural killer (NK) cells to treat cancer, infectious diseases and other diseases, today announced that...
Incyte Announces First Patient Treated in Phase 3 Clinical Trial of Pemigatinib as a First-Line Therapy for Cholangiocarcinoma
- Incyte (Nasdaq:INCY) today announced that the first patient has been treated in FIGHT-302, an open-label Phase 3 study evaluating pemigatinib (INCB54828), its selective fibroblast growth factor receptor (FGFR) inhibitor, compared to gemcitabine with cisplatin...
Unreported Clinical Trials Threaten Credibility of Published Studies
Large trials that go unreported threaten the credibility of available, published evidence and are detrimental to the scientific process, according to a brief research report and an editorial published in Annals of Internal Medicine. Researchers identified the 500...
Abivax Receives First Clinical Trial Authorization for ABX464 Phase 2a Study in Patients with Rheumatoid Arthritis
French agency (ANSM) first to approve clinical trial with ABX464 in moderate to severe rheumatoid arthritis Trial to be conducted in 60 patients in five countries, with “first patient in” scheduled for early Q3 2019 Rheumatoid arthritis is a severe, debilitating...
China approves first norovirus vaccine for clinical trial
Chinese authorities have greenlighted the clinical trial for the world's first tetravalent vaccine against norovirus, the most common cause for viral gastroenteritis. The vaccine received the clinical research permit from the National Medical Products Administration...
ObsEva SA Announces Completion of Patient Recruitment in IMPLANT 4 Phase 3 Clinical Trial of Nolasiban for Improving IVF Outcomes
ObsEva SA (NASDAQ: OBSV / SIX: OBSN), a clinical-stage biopharmaceutical company focused on the development and commercialization of novel therapeutics for serious conditions that compromise a woman's reproductive health and pregnancy, today reported completion of...
Georgetown University Launches Clinical Trial for Lewy Body Dementia
– Georgetown University Medical Center announces the launch of the only known therapeutic (disease modifying) clinical trial for Lewy body dementia, a neurological disorder that affects a million people in the United States for which there are no approved medications...
Adastra Pharmaceuticals Announces Positive Interim Data from Phase 1b Clinical Trial of Zotiraciclib in the Treatment of Recurrent Malignant Gliomas
National Cancer Institute (NCI) Study Designed to Investigate Zotiraciclib in Combination with Temozolomide (TMZ) Presented During Poster Session at ASCO 2019 Maximum Tolerated Dose of Zotiraciclib (250mg) Elicits Tumor Reduction, Suggesting Activity in Glioblastoma...
Compugen Presents Update on COM701 Phase 1 Trial at the 2019 ASCO Annual Meeting
HOLON, Israel, June 3, 2019 /PRNewswire/ -- Compugen Ltd. (CGEN), a clinical-stage cancer immunotherapy company and leader in predictive target discovery, today announced that its ongoing Phase 1 clinical trial evaluating COM701, a first-in-class therapeutic antibody...
Epizyme Reports Updated Data from Phase 2 Trial of Tazemetostat for Epithelioid Sarcoma at 2019 ASCO Annual Meeting
New Clinical Data Presented Today Included in Recently Submitted NDA to FDA Epizyme, Inc. (EPZM), a late-stage biopharmaceutical company developing novel epigenetic therapies, today reported updated data on tazemetostat from the epithelioid sarcoma cohort of its...
Impact of Electronically Accessible Pathways on Clinical Trial Enrollment at a Large Multisite Cancer Center
A presentation at the ASCO Annual Meeting (June 2, 2019; Chicago, IL) explored the role that the clinical pathways program at the Levine Cancer Institute (Charlotte, NC) plays in clinical trial enrollment. Researchers from Levine Cancer Institute said that clinical...
Pivotal Phase 3 ARTEMIS Trial Data Demonstrates Consistent Safety and Efficacy of AR101 in Children and Adolescents with Peanut Allergy
Aimmune Therapeutics, Inc. (Nasdaq: AIMT), a biopharmaceutical company developing treatments for life-threatening food allergies, today presented topline results from the pivotal European Phase 3 ARTEMIS clinical trial, which it previously announced had met its...
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