Latest News on Clinical Trials
Smith & Nephew Adopts One-platform Approach with Medidata to Support Expansion of Study Portfolio
Medidata (NASDAQ: MDSO) today announced that medical technology business Smith & Nephew (LSE: SN, NYSE: SNN) has consolidated all of its global studies on the Medidata Rave Clinical Cloud. The company expanded its use of Rave clinical solutions and will leverage...
3-V Biosciences Commences Dosing in Phase 2 Clinical Study of the FASN Inhibitor TVB-2640 in Patients with NASH
3-V Biosciences, Inc. (3-V Biosciences) and Ascletis Pharma Inc. (Ascletis, 1672.HK) announced that 3-V Biosciences has recently dosed its first patient in a Phase 2 clinical trial of the FASN (fatty acid synthase) inhibitor TVB-2640 (Ascletis code: ASC40) in patients...
Xeris Pharmaceuticals Announces Results From a Phase 1 Study of Its Novel Formulation of Diazepam
Xeris Pharmaceuticals, Inc. (XERS), a specialty pharmaceutical company leveraging its novel technology platforms to develop and commercialize ready-to-use injectable and infusible drug formulations, today announced positive findings from a Phase 1 study of its novel...
L-DOS47 Phase II Randomized Study Advances to Second Cohort
Helix BioPharma Corp. (TSX: HBP), (“Helix” or the “Company”), an immuno-oncology company developing innovative drug candidates for the prevention and treatment of cancer, has announced that the Trial Steering Committee ("TSC") reviewed safety data from the first...
Watchful waiting reasonable for patients with diabetic macular edema and good vision
NIH-funded clinical trial finds starting treatment prior to vision loss unnecessary for most people; close monitoring essential. People with good vision despite having center-involved diabetic macular edema can safely forego immediate treatment of their eye condition...
$4.6 million grant funds clinical trial of stem cell immunotherapy for metastatic sarcoma and other hard-to-treat cancers
Scientists at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have been awarded a $4.6 million grant from the California Institute for Regenerative Medicine - also known as CIRM - to support a phase I clinical trial of a novel...
Medicenna Announces Completion of Enrolment in MDNA55 Phase 2b Recurrent Glioblastoma Clinical Study
Interim Top-Line Results to be Announced in June, 2019 TORONTO and HOUSTON, April 30, 2019 /PRNewswire/ - Medicenna Therapeutics Corp.("Medicenna" or the "Company") (TSX: MDNA; OTCQB: MDNAF), a clinical stage immuno-oncology company, is pleased to announce that it has...
Report: Health Economics Outcomes are Rarely Considered in Adaptive Clinical Trial Designs
Opportunities Are Potentially Being Missed to Improve Healthcare Decision Making —Value in Health, the official journal of ISPOR—the professional society for health economics and outcomes research, announced today the publication of new research showing that...
Intec Pharma Reports Last Patient Last Visit in Pivotal Phase 3 Trial of Accordion Pill™ Carbidopa/Levodopa for the Treatment of Advanced Parkinson’s Disease Patients
Company on track to report top-line data in July/August time frame Intec Pharma Ltd. (NASDAQ: NTEC) ("Intec" or "the Company") today announces that the last patient has completed their final visit in the Company's pivotal Phase 3 trial (the ACCORDANCE trial)...
Abivax Receives First Phase 2b Ulcerative Colitis Clinical Trial Authorization, Provides Update on Progress of ABX464 Clinical Development Plan in Inflammatory Diseases
ABX464 advancing into Phase 2b dose-finding trial in ulcerative colitis, to be conducted in 232 patients with moderate to severe disease in up to 150 study sites in >15 countries Study recently fully authorized in Canada as first country, with First Patient in...
Allotex Announces Commencement of Final Phase of Presbyopia Clinical Trials
Allotex, a Boston based private company developing the TransForm Corneal Allograft (TCA) for the treatment of presbyopia (reading glasses) and hyperopia (far sightedness), is pleased to report that over 50 eyes have been treated in the first phase of its clinical...
3-V Biosciences Commences Dosing in Phase 2 Clinical Study of the FASN Inhibitor TVB-2640 in Patients with NASH
3-V Biosciences, Inc. (3-V Biosciences) and Ascletis Pharma Inc. (Ascletis, 1672.HK) announced today that 3-V Biosciences has recently dosed its first patient in a Phase 2 clinical trial of the FASN (fatty acid synthase) inhibitor TVB-2640 (Ascletis code: ASC40) in...
XORTX Provides Overview and Announces $5 Million Financing to Advance Clinical Trials
Pivotal Registration Clinical Study with XRx-008 and Phase 2b Clinical Study withTMX-049 Planned in 2020 XORTX Therapeutics Inc. ("XORTX" or the “Company”) (CSE: XRX; OTCQB: XRTXF), a biopharmaceutical company focused on developing innovative therapies to treat...
Trial finds heart drugs could help prevent stroke and dementia
A small clinical trial by researchers at the University of Edinburgh in the UK has showed that cilostazol and isosorbide mononitrate could prevent recurrence of stroke and vascular dementia. The drugs are currently used to treat heart disease and angina, among other...
ISCO’s Phase 1 Trial Testing Neural Stem Cell Therapy Completes Patient Enrollment
Patient enrollment and dosing is now complete for International Stem Cell Corporation’s (ISCO) Phase 1 trial testing its ISC-hpNSC neural stem cells — a cellular therapy that offers a new approach for treating Parkinson’s disease. “We are excited to announce the...
Cerevance Achieves Key Endpoints in Phase 1 Clinical Trial of Novel Parkinson’s Disease Drug CVN424
Results Demonstrate Safety of CVN424 and Enable Initiation of Phase 2 Study in Patients Cerevance, a clinical stage biopharmaceutical company advancing new medicines for brain diseases, has successfully completed its Phase 1 clinical trial of CVN424, the company’s...
BioVie Achieves Primary Objectives in Phase 2a Clinical Trial of BIV201 in Refractory Ascites
BioVie Inc. (BIVI) (“BioVie” or “Company”), a clinical-stage company developing innovative drug therapies for liver disease, today announced top-line results for its Phase 2a clinical trial of BIV201 (continuous infusion terlipressin) in six patients with refractory...
International Stem Cell Corporation Completes Enrollment and Dosing in its Parkinson’s Disease Clinical Trial
International Stem Cell Corporation (OTCQX: ISCO) (www.internationalstemcell.com) (“ISCO” or “the Company”), a California-based clinical stage biotechnology company developing stem cell-based therapies and biomedical products, announced today the completion of subject...
Clinical Trial Results from MyoKardia’s Phase 2 PIONEER-HCM Study of Mavacamten Published in the Annals of Internal Medicine
Mavacamten is Being Developed to Treat the Most Common Inherited Form of Heart Disease, Hypertrophic Cardiomyopathy, for Which No Targeted Medical Therapies Exist Twelve-Week Treatment with Mavacamten Demonstrated Reductions in Obstruction and Improvements in Patient...
First-in-human trial shows promise in treating neuroblastoma
Neuroblastoma is the most common extracranial solid cancer in children, and patients with high-risk disease are challenging to treat. In a promising development, researchers at Baylor College of Medicine released initial findings from the first two patients treated in...
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