Latest News on Clinical Trials
Principia Biopharma Presents Phase 1 Clinical Data from CNS Penetrating BTK Inhibitor Candidate PRN2246/SAR442168 at ACTRIMS 2019
-- Orally administered PRN2246 achieved full BTK occupancy in peripheral blood -- -- PRN2246 exhibited blood-brain barrier permeability and CNS exposure -- -- Sanofi to lead Phase 2 development for people with Multiple Sclerosis -- SOUTH SAN FRANCISCO, Calif., March...
Concert Pharmaceuticals Presents Interim CTP-543 Phase 2 Data in Alopecia Areata during Late-Breaker Session at American Academy of Dermatology Annual Meeting
-Concert Pharmaceuticals, Inc. (NASDAQ: CNCE) today announced that interim results from its Phase 2 clinical trial evaluating its product candidate CTP-543 in patients with moderate-to-severe alopecia areata will be presented in an oral presentation during the...
Lupus Therapeutics Partners with Takeda on Phase 1 Trial
Testing Potential Treatment for Lupus The Lupus Research Alliance and its affiliate, Lupus Therapeutics announced a collaboration with Takeda Pharmaceutical Company Limited, to evaluate the investigational biologic TAK-079 as a potential new therapy for lupus in a...
Compugen Presents Update on COM701 Phase 1 Trial at ASCO-SITC Clinical Immuno-Oncology Symposium
Completion of enrollment of both monotherapy and dual combination dose escalation arms expected in 2019 Compugen Ltd. (NASDAQ: CGEN), a clinical-stage cancer immunotherapy company and leader in predictive target discovery, today announced that its Phase 1 clinical...
Aesculap Biologics, LLC Reaches Halfway Mark for Enrollment in Pivotal Phase 3 Clinical Trial of NOVOCART® 3D in Patients with Articular Cartilage Defects of the Knee
Aesculap Biologics, LLC ("Aesculap Biologics") announced today that it has successfully achieved 50 percent enrollment in the ongoing Phase 3 clinical trial of NOVOCART® 3D, an autologous chondrocyte transplantation system designed to treat articular cartilage defects...
Syndax Announces Clinical Data from its Entinostat Immuno-oncology Program Selected for Two Oral Presentations at the American Association for Cancer Research Annual Meeting 2019
Syndax Pharmaceuticals, Inc. ("Syndax," the "Company" or "we") (Nasdaq: SNDX), a clinical stage biopharmaceutical company developing an innovative pipeline of cancer therapies, today announced two oral presentations at the upcoming American Association for Cancer...
Trovagene to Present Data from Lead Clinical Programs of Onvansertib in AML and mCRPC at the American Association for Cancer Research Annual Meeting
Trovagene, Inc. (Nasdaq: TROV), a clinical-stage oncology therapeutics company, taking a precision medicine approach to develop drugs that target cell division (mitosis) for the treatment of leukemias, lymphomas and solid tumor cancers, today announced that two...
Aldeyra Therapeutics Provides Update on Ophthalmic Programs at 2019 Research & Development Day
Phase 3 Results from ALLEVIATE Trial in Allergic Conjunctivitis Expected in Early 2019 Co-Primary Endpoints Confirmed for Phase 3 Clinical Trial in Dry Eye Disease, Expected to Begin in First Half of 2019 Phase 3 Clinical Trial of ADX-2191 in Proliferative...
C-Path, FARA launch Friedreich’s Ataxia Clinical Database for Development of Treatments
Critical Path Institute's (C-Path) Data Collaboration Center (DCC) and the Friedreich's Ataxia Research Alliance (FARA) today announced the launch of the Friedreich's Ataxia Integrated Clinical Database (FAICD). The new platform will enable collaborative research and...
A University of Nebraska-Lincoln Clinical Trial on Natreon’s Patented PrimaVie® (Shilajit) Showed Increased Retention of Muscular Strength and Decreased Hydroxyproline
Natreon's Patented PrimaVie® (Shilajit) Promoted the Retention of Muscular Strength and a Decrease in Hydroxyproline (a marker of collagen degradation) in a Recently Published Clinical Trial at The University of Nebraska-Lincoln. Natreon, a leader in Ayurvedic...
Hound Labs Announces Results From Second Clinical Trial with the University of California, San Francisco
Hound Labs, Inc., a leader in the field of breath diagnostics, today announced results of its second clinical trial with the University of California, San Francisco (UCSF), in which researchers measured THC 1 in breath. Results from this landmark study confirm – for...
Noxxon Files Application for Phase 1/2 Clinical Trial Combining NOX-A12 & Radiotherapy for the Treatment of Brain Cancer Patients
Company aims to be ready to launch the trial in Q2-2019 NOXXON Pharma N.V. (Euronext Growth Paris: ALNOX), a biotechnology company focused on improving cancer treatments by targeting the tumor microenvironment (TME), announced today that it has filed the clinical...
Stero Biotechs to Commence Phase 2 Clinical Trial of ST-AH-01 Cannabidiol Formulation for Ground Breaking Maintenance Therapy and Steroid Reduction in Patients With Autoimmune Hepatitis
Stero Biotechs has received Ethics Committee approval by Israel'sMinistry of Health and will soon enroll the first patients in a ground-breaking study to use CBD to reduce steroids in patients with liver disease. Stero discovered that by introducing CBD to patients...
NewLink Genetics Announces Clinical Trial Abstract Presentation at AACR Annual Meeting
NewLink Genetics Corporation (NASDAQ:NLNK) today announced that a late-breaking abstract reporting results from a Phase 2 study of NLG207, a nanoparticle formulation of the topoisomerase 1 inhibitor, camptothecin, has been accepted for poster presentation at the...
First Patient Dosed in a Clinical Trial of Tyvyt® (Sintilimab injection) in Combination with IBI305 as First Line Treatment for Patients with Advanced Hepatocellular Carcinoma
Innovent Biologics, Inc. (Innovent) (HKEX: 01801) today announced that the first patient has been dosed in ORIENT-32, a trial that evaluates Tyvyt® (generic name: sintilimab injection), a fully human anti-programmed cell death protein 1 (anti-PD-1) monoclonal...
LumiThera Receives Notice of Award for $2.5 Million National Eye Institute Grant to Support U.S. Multi-Center Clinical Trial for Treating Dry Age-Related Macular Degeneration
LumiThera Inc., a commercial stage medical device company creating a photobiomodulation (PBM) treatment for ocular disorders and disease, today announced it is a recipient of a small business innovative research (SBIR) phase II grant from the National Institute of...
Cellectar Reports Positive Top-line Response Rate of 30% from R/R Multiple Myeloma Cohort in Ongoing Phase 2 Study of CLR 131
Company’s lead product candidate previously demonstrated positive top-line results from the diffuse large B-cell lymphoma cohort of this study Dosing in multiple tumor types is ongoing; Cellectar intends to report additional data this year Cellectar Biosciences, Inc....
Maximizing Clinical Trial Performance Using New Protocol Design Practices: A New Webinar Hosted by Xtalks
Protocol design can have a significant impact on patient engagement and clinical trial performance. In this live webinar, explore the findings of a recent scholarly study conducted by the Center for the Study of Drug Development (CSDD) at Tufts University School of...
LYNPARZA® (olaparib) Reduced the Risk of Disease Progression or Death as 1st-Line Maintenance Treatment in Germline BRCA-Mutated Metastatic Pancreatic Cancer
Phase III POLO Trial Met Primary Endpoint of Progression-Free Survival AstraZeneca and Merck’s LYNPARZA is the first PARP inhibitor to demonstrate benefit in gBRCAm metastatic pancreatic cancer in a Phase III Trial AstraZeneca and Merck & Co., Inc.,...
Asana BioSciences Strengthens Leadership Team as ASN002 Phase 2b RADIANT Trial in Atopic Dermatitis Advances with a Second Positive DSMB Recommendation
Appointment of Shashank Mahashabde as VP of CMC and Pablo Jimenez, MD FAPCR as VP and Therapeutic Area Head of Immunology Asana BioSciences, a clinical stage biopharmaceutical company focused on discovery and development of innovative medicines in...
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